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The U.S. Food and Drug Administration has approved a generic version of the world’s only twice-a-year shot to prevent HIV. This is a big step toward making the extremely effective drug available inexpensively and quickly in 120 low- and middle-income countries. The drug, called lenacapavir, is expected to cost $40 a person each year in these places, the same price as daily preventive pills available now. But the shots are much more convenient than the pills because they’re needed much less frequently. The generic will not be available in the U.S. because there is a brand-name version still protected by a patent.

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FILE - This colorized electron microscope image released by the National Institute of Allergy and Infectious Diseases on March 26, 2024, shows avian influenza A H5N1 virus particles (yellow), grown in Madin-Darby Canine Kidney (MDCK) epithelial cells (blue). (CDC/NIAID via AP, File)

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A nurse prepares a syringe before injecting a patient with the new HIV prevention drug lenacapavir at the ART clinic at Mbarara City Council Health Center IV in western Uganda, Aug. 21, 2026. (AP Photo/Hajarah Nalwadda)

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Patients wait for services at the ART clinic at Mbarara City Council Health Center IV in Mbarara, western Uganda, Aug. 21, 2026. (AP Photo/Hajarah Nalwadda)

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A health flyer educating about HIV prevention is seen at the ART clinic at Mbarara City Council Health Center IV in western Uganda, Aug. 21, 2026. (AP Photo/Hajarah Nalwadda)

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A health worker registers patients at the ART clinic at Mbarara City Council Health Center IV in Mbarara, western Uganda, Aug. 21, 2026. (AP Photo/Hajarah Nalwadda)