APTOPIX Commanders 49ers Football

Washington Commanders wide receiver Treylon Burks (13) cannot catch a pass while being defended by San Francisco 49ers safety Malik Mustapha (6) during the second half of an NFL football game in Santa Clara, Calif., Monday, Oct. 19, 2026.

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Purdy and the 49ers build a big lead and hold on to beat the Commanders 23-17

Purdy and the 49ers build a big lead and hold on to beat the Commanders 23-17

Brock Purdy threw a touchdown pass, Christian McCaffrey ran for two scores and the San Francisco 49ers held on to beat the Washington Commanders 23-17 for their sixth straight win to open the season. The Niners built a 20-point lead and held off the Commanders with two late defensive stops. Jayden Daniels threw two touchdown passes in the second half to cut a 20-point deficit to 23-17, but Malik Mustapha broke up a fourth-down pass to Treylon Burks near the goal line with 1:54 to play to preserve the lead. Washington got the ball back but Daniels was sacked on the final play.